Home Page

Papers

Submissions

News

Editorial Board

Open Source Software

Proceedings (PMLR)

Transactions (TMLR)

Search

Statistics

Login

Frequently Asked Questions

Contact Us



RSS Feed

Time-to-Event Prediction with Neural Networks and Cox Regression

Håvard Kvamme, Ørnulf Borgan, Ida Scheel; 20(129):1−30, 2019.

Abstract

New methods for time-to-event prediction are proposed by extending the Cox proportional hazards model with neural networks. Building on methodology from nested case-control studies, we propose a loss function that scales well to large data sets and enables fitting of both proportional and non-proportional extensions of the Cox model. Through simulation studies, the proposed loss function is verified to be a good approximation for the Cox partial log-likelihood. The proposed methodology is compared to existing methodologies on real-world data sets and is found to be highly competitive, typically yielding the best performance in terms of Brier score and binomial log-likelihood. A python package for the proposed methods is available at https://github.com/havakv/pycox.

[abs][pdf][bib]       
© JMLR 2019. (edit, beta)